Cellular and Molecular Brain Research Laboratory and Pam Quirk Brain Health and Biomarker Discovery Laboratory
Amanda M. Leisgang Osse, B.S., is a graduate student in the Cellular and Molecular Brain Research Laboratory and Pam Quirk Brain Health and Biomarker Discovery Laboratory in collaboration with the Chambers-Grundy Center for Transformative Neuroscience in the Department of Brain Health at the University of Nevada Las Vegas. She has been an asset to investigations related to biomarker discovery for Alzheimer's disease, in both clinical and preclinical samples. Applying cutting edge techniques, she evaluates Alzheimer's disease patient samples for candidate biomarkers of risk, diagnosis, and progression. Amanda's research projects also include evaluations of preclinical Alzheimer's disease models for better understanding of cellular and molecular alterations in disease verses non-disease states, as well as testing novel therapeutics. A large focus of Amanda's studies is on the involvement of neuroinflammation and risk factors for Alzheimer's disease, including gender and diabetes. Amanda's translational approach advances basic understanding of disease mechanisms and extends these findings into the discovery of novel biomarkers and development of new treatments.
Amanda has received several awards for her research, including the Nathan J. Lindsay Brain Health Endowed Fellowship, the Mary S. And D. Keith Kleven P.T., M.S. Endowed Scholarship, and UNLV's Summer Doctoral Fellowship. She has authored several peer-reviewed journal articles and was an invited author for a book chapter on the role of preclinical models in Alzheimer's disease drug development. Amanda has held leadership positions in numerous UNLV organizations and is a founding member of the Association for Women in Science (AWIS) Nevada Chapter.